Endocrine Abstracts

Ghrelin is a 28 amino acid n-octanoylated peptide which is the natural agonist for the growth hormone secretagogue receptor and which potently stimulates GH release in vivo (1). We studied the effects of a somatostatin infusion on Ghrelin release in normal subjects.STUDY PROTOCOLFour females and five males, 25-40 years of age, body mass index < 28 kg per m2 were studied. Local ethics committee permission was obtained for ...

Ghrelin is an acylated peptide hormone that is expressed by a variety of tissues including the stomach, hypothalamus and kidney. Ghrelin produces a range of effects, including stimulating the release of growth hormone from the pituitary gland, and inducing feeding and obesity.The effects of some hormones can be altered by interactions with other proteins; so the aim of this project was to screen plasma for proteins that can bind ghrelin, as part of an i...